Disorders of thyroid function in the course of chronic Lyme infections are manifested first of all by a reduced concentration of triiodothyinine (low T3 syndrome).
The causes of these phenomena are: accumulation of toxins and inflammation caused by infection. For the thyroid to produce a natural T4 hormone, it needs tyrosine, which the body extracts from protein and iodine. The tyrosine deficiency disturbs the synthesis of many important substances, including:
– Adrenaline (regulates the level of glucose in blood and plays a decisive role in the mechanism of stress, that is, the rapid reaction of the human body to the threat, manifested by accelerated heartbeat, increased blood pressure, enlargement of the bronchi and pupils);
– Dopamine (affects coordination and muscle tension, controls mental and emotional processes, regulates the secretion of growth hormone, prolactin and gonadotropins);
– Thyroxine – thyroid hormone (it participates in the metabolic processes of the whole body, e.g. glucose absorption and breakdown of fats, affects the work of the gonads, lactation and regulates fertility);
– Norepinephrine (it separates with adrenaline, sharpens alertness, stimulates and concentrates, and sharpens memory).
Tyrosine is one of the most important amino acids for the human body,
i.e. organic compounds necessary for the proper functioning of the body, regulating cellular metabolism, used for the synthesis of endogenous proteins, hormones and neurotransmitters. Tyrosine and thyroid are related to each other, because the amino acid plays an important role in the proper functioning of the thyroid – it connects with the atomic iodine and in this way precursors of the proper hormones, especially T4, are formed. A deficiency of tyrosine induces hypothyroidism, which may be manifested, among others, permanent fatigue and exhaustion. Tyrosine supplementation should be consulted with a physician.
When T4 loses one iodine atom, it converts to T3 and the processed hormone thus supplies our cells throughout the body. Proper conversion in Lyme disease is often disrupted, so you should be encouraged by certain precursors and cofactors.
* P5P – The active form of vitamin B6, which is metabolically active. It acts as a coenzyme helping our enzymes to perform their functions. Participates in T4 conversion. In a healthy person, the body calmly deals with the transformation of the inactive form of B6 to the metabolically active one, which is P5P. However, in Lyme patients, it can be a serious problem. P5P works with organic zinc, which is also essential for the thyroid hormone to be active and useful. Zinc is crucial in the activation of T4 to T3 in the liver and kidneys and improves the action of certain enzymes (deiodinases) that activate thyroid hormone.
* Catalase – Is an antioxidant that reduces hydrogen peroxide produced in the liver. It changes hydrogen peroxide into water and oxygen in milliseconds. We observe high levels of hydrogen peroxide in people with thyroid disorders, so neutralization is necessary, especially at Hashimoto. The liver is the lion’s share of T4 conversion, which can effectively disrupt hydrogen peroxide.
* Selenium – Like zinc, this mineral is also needed for some deiodinase enzymes that convert T4 to T3. Selenium is also needed to balance excessive thyroid activity, which can be caused by internal or external stress factors. And finally, selenium is a powerful antioxidant.
Greater antioxidant activity means less inflammation, and inflammation means better thyroid function, because inflammation can make thyroid hormone lazy.
* Probiotics – Up to 20% of inactive T4 is converted into T3 in our intestines. Many Lyme sufferers have a serious intestinal problem and intestinal microflora dysfunction, or dysbiosis.
* Methylcobalamin – It is one of the active forms of vitamin B12. B12 deficiency goes hand in hand with hypothyroidism! Research suggests that as many as 40% of patients with hypothyroidism also have a deficiency of vitamin B12. Low levels of vitamin B12 adversely affect the amount of thyroid hormone production.
* Ashwagandha – Stimulates the production of both T4 and T3 in the body. It also supports the adrenal glands and protects the thyroid against DNA changes.
* Iodine – Here we will stop for a moment.
There is a mass confusion and paranoia in the subject of iodine. The belief among physicians that iodinated salt meets the body’s need for iodine is common. Although iodized salt is in fact the most effective public health initiative to reduce iodine deficiency, it is impractical in the face of hypothyroidism. Iodine is essential for normal thyroid function and proper production of thyroid hormones. It is also necessary for the correct conversion of T4 to T3.
Not only the thyroid uses iodine, it is needed for all cells, and each cell has a unique receptor programmed for iodine. Iodine is especially important for healthy breasts and prostate. The risk of reproductive cancer becomes much higher with low iodine levels. If only salt is the main source of iodine, you should eat enough iodized salt to get the right amount of iodine, which will lead to rapid sodium levels, which is not a good idea. In addition, typical table salt is deprived of 80% of minerals.
Iodine supplementation can improve your health at every level. Iodine is needed for trillions of cells, the whole organism uses it, in all organs. Fear of iodine leaves many innocent patients who blindly trust the doctors, unaware. Iodine deficiency is a risk factor for thyroid cancer and causes or at least contributes to hypothyroidism, cancer and autoimmune diseases such as Hashimoto. The status of iodine determines the growth of warts. Goals and nodules are caused by iodine deficiency. Iodine supports our reproductive organs.
The enriched iodized salt contains only iodide. That’s only half of what the body needs. Iodide must be transformed into iodine, but not all organisms can cope with it. Then there are problems with breasts in women and in men with prostate. We test the level of iodine by examining urine and blood. In the blood we check the level of “thyroglobulin”, or in briefTg. Thyroglobulin blood tests are a more sensitive biomarker of iodine status than thyrotropin or thyroid hormones such as T3 (triiodothyronine) and / or T4 (thyroxine). Reception of iodine in the absence of selenium can be very harmful. The use and supplementation of iodine while taking hormones on your own is not recommended and dangerous.