(Mycoplasma) genitalium, hominis, pneumoniae and others – the most dangerous bacterium on this planet causing, among others, amyotrophic lateral sclerosis
Mycoplasma pneumoniae (as well as other subspecies) is an extremely small gram-negative bacterium without a bacterial wall. Approximately 4000 mycoplasma bacteria can penetrate into one erythrocyte (red blood cell) vs. e.g. 12 bartonella bacteria, which can fit into one such cell – already this fact alone shows that this bacterium can penetrate absolutely everywhere, to anywhere in the body. Mycoplasma is from 200 kinds – Pneumoniae, Hominis and Genitalium are the most popular. Mycoplasma infection starts with a normal cough and it is a recurrent infection (it often appears in people regularly, e.g. every month and it is not known what it is – so I suggest – check M. pneumoniae and hominis, which is a typical genital / urinary tract infection) causes inflammation of the respiratory system). An untrained person or even a physician does not distinguish it from streptococcus because, apart from throat problems, such as thirst, inflammations of the throat including tonsils (such a common cold / flu) appear. This can lead to chills (like in bartonella) or headaches and stuffy sinuses / nose. There may also be diarrhea, dizziness or even vomiting for no apparent reason.The classic symptom for this bacterium is chest pains, sometimes skin rash, earache, enlarged lymph nodes and conjunctivitis. It is not uncommon to have conjunctivitis, iris, ocular myasthenia or in the worst case – permanent eye damage. In 10% of people, there is heart failure with its inflammation, pericarditis, thrombus, Kawasaki disease. Neuro problems are demyelination of the nerve sheaths which is not at all uncommon!, encephalitis, meninges, cerebellum, transverse myelitis, Guillain-Barr syndrome, cranial and peripheral neuropathy, diplopia, stroke, psychiatric disorder, facial nerve palsy, confusion speech, acute psychosis or Tourett syndrome and epilepsy. Mycoplasma kills – leading to amyotrophic lateral sclerosis. Disorders of the digestive system also appear in the case of this infection such as loss of appetite, abdominal pain or even beyond this system – glomerulonephritis or Still’s disease. If someone has arthritis with swelling – the first thing my suspicion is about is mycoplasma. Other symptoms of mycoplasma are anemia, thrombotic purpura, Raynaud’s syndrome, inflammation of blood vessels, muscle and joint pain, inflammation of the kidneys, rashes / erythema, Stevens-Johnson syndrome.
Transmitted through sperm during a classic and oral intercourse. Often, this bacterium causes problems with prostate (prostatitis) in 5% of men.
Mykoplasmafermentans – found in genitalia as well as in the respiratory system. It can cause cough, joint damage, cancer, leukemia, chronic fatigue, fibromyalgia, memory problems, headaches, depression, diarrhea, irritability, intestinal overflow, skin rashes. It is a very popular bacterium in SLA. During the Iraq war, half of the US soldiers showed a positive result in tests for this bacteria (so-called Gulf War syndrome – I think a lot of people associate these vaccine / bacterial tests with American soldiers at that time).
Mycoplasma penetrans – causes blood clots in the veins, anemia, inflammation of the urethra, respiratory system including severe breathing disorders, rheumatoid arthritis. It often appears in SLA. It can result in a stillbirth, miscarriage, premature delivery and severe preeclampsia in women. It also causes inflammation of the vagina. Standard – transmitted by sperm in any type of intercourse.
Mycoplasma Salivarium – the typical place of living is the mouth. It causes joint disorders as well as their pain, gingivitis and periodontal disease as well as jaws, ovarian cancer, brain abscesses or chronic gastritis.
Mycoplasma orale – also lives in the mouth. It infects the synovial fluid and will also damage joints (often found in RA) and bone marrow.
Mycoplasma pirum – often occurs in people with AIDS, causes urinary tract infections, respiratory infections and chronic fatigue. In the USA, about 25-60% of cats carry this bacteria, it is also popular in cow’s milk, and boiling of such milk seems to be very important in the prevention of its infection (mycoplasma is resistant to very low temperatures). It can also be found in food (also thorough washing can help). In general, mycoplasma feeds on everything – sugar (fructose, mannose, maltose, ribose, glycogen, starch –is it just me or did anybody else think about the keto diet :-)?), Vitamin B2. Amino acids, proline, serine, tryptophan, tyrosine, methionine, glutamine – literally everything! (including minerals or vitamins A and E, hence also eye problems). What’s worse, mycoplasma feeds on choline breaking down phosphotylcholine to choline and palmitic acid (hence, memory problems).However, my biggest challenge in providing possible help for people with ALS, is inhibition of mycoplasma’s production of the enzyme sphingomyelinase (ASM) – it is an enzyme that breaks down spingomyelin. It is a substance found in the myelin casing of the neuron axon – without this substance, neurodegeneration and rapid progression of amyotrophic lateral sclerosis occurs.
On the other hand, the breakdown of phosphotylglycerol causes high levels of glycerol (a type of alcohol) which can cause mental fog. Activates collagenase (breaks down collagen, among others, in synovial fluid or skin) or breaks down hyaluronic acid (activating hyaluronidase).
For example, if the mycoplasma feeds only on arginineat the moment – it will be consumed quickly in the body resulting in dementia problems, encephalopathy, a strong surplus of ammonia (another bacterium that may cause ureliticumureoplasm, about which I will write more soon) in the body and dysregulation of neurotransmitters.Mycoplasma also extracts energy (ATP) directly from the mitochondria, damaging them. When killing cells, ATP releases into the bloodstream and activates P2X(7) receptors that activate mast cells. This increases intracellular calcium levels and the production of an inflammatory cytokine IL-1beta. The mere activation of P2X(7) receptors contributes to atherosclerosis and chronic pain. In turn, ATP causes an increase in COX-2 (causes inflammation in the brain) and prostaglandins E2 (PGE2) in astrocytes. This can lead to inflammation in the brain.
The mycoplasma does not have a cell wall but they have a so-called cytoplasmic membrane, that contains various lipoproteins – for example, choline-containing lipids in mycoplasma cause adherence of this bacterium to the cell / tissue walls and stimulate the production of inflammatory states (TNF alpha cytokines).Some species may produce arachidonic acid. Almost immediately after joining the cell mycoplasma inhibits its apoptosis – thanks to this, it can draw food from it. One of the mechanisms of this action is to increase the activity of calpastatin. Calpastatin inhibits the production of calpain, of which there are several forms, and one of them is a protease that participates in the vital function of the cell. Calpain is also involved in the survival of neurons and memory. Mycoplasma can also reduce TNF alpha (inflammatory cytokine) by 60% or caspase-8 (a protein that causes cell death – it should be stimulated during cancer).
Generally speaking, mycoplasma predominantly stimulates TNF-alpha, TNF beta, IL-8, IL-6, IL-1beta and they are strongly generated during active mycoplasma infection. For example, TNF alpha can be activated 200 – 500x above the norm (I had it!). Then the P2X(7) receptors stimulate the phosphatidylserin, a lipid that is found in the cell membrane, and this activates the immune system. The stimulation of COX2, PGE2 and inhibition of catalase (i.e., inflammation levels go up and antioxidant protection levelsgo down) occurs.
PGE2 reduces bronchiectasis, causes narrowing / tension or loosens muscles of the digestive system, is responsible for the production of gastric acid (now you know how easy it can lead to the reactivation of Helicobater pylori or to SIBO). It is responsible for uterine contractions, stimulates platelets, causes hypersensitivity to pain. Also, active mycoplasma can cause miscarriage (strong uterine contractions stimulating PGE2 2.5 to 4.5 times).
Mycoplasma inhibiting catalase by 2/3 causes an increase in peroxidase hydrogen (oxidant) – it causes an increase in inflammation or premature rupture of mucous membranes.
IL-6 is one of the cytokines raised by mycoplasma. Like COX-2, it is involved in the production of PGE2 progstaglandin, especially in the brain and hippocampus (causing fever during infection). Mycoplasma causes an increase in CD40.86,54,83,25 cells, CCR7, CD1a, CD123 and HLA-ABC, HLA-DR or MCP-1,2, GM-CSF and decreases CD4+ cells (that is what the HIV virus also reduces, hence the frequent connection of HIV + mycoplasma) – generally everything that is possible which stimulates inflammation – then Mycoplasma turns it up.
It also increases the level of IL-17 (cytokines responsible for a very large number of diseases from the group of autoimmune diseases) and increases hepcidin – it is a hormone that reduces iron levels to starve the bacteria (which of course in the case of mycoplasma completely will not give anything – hence the anemia in the case of active mycoplasma infection). Anemia, for example, also occurs through increased calcium activity, depletion of ATP and excess of oxidants.
Protocol of an American herbalist / phytotherapist for mycoplasma pneumonia (and other varieties)
Cordyceps – tincture, 1/4 teaspoons 3x a day, capsules 2 grams 3x a day
Isatis – tincture as the strongest, 1/2 teaspoon 3x a day
Baikal thyroid – tincture 1/4 teaspoon 3x a day or capsules 1gram 3x daily
Houttuynia – tincture, 1/4 teaspoon 3x a day
SidaAcuta – tincture – 30 drops 3x a day
NAC – 2 grams in the morning, 2 grams before bedtime
Vitamin E (alpha tocopherol) – 200 units or 150 mg per day
Olive oil (including olive leaf)
Shisandra + Siberian ginseng + Rhodiola – tincture 1/2 teaspoon 3x daily
In case of additional problems with the urinary system:
– UVA ursi and phellodendron – tincture1/4 teaspoon 3 times a day for 30 days
– Bidenspilosa – tincture 1/4 teaspoon 3x a day for 30 days
With cervical / vaginal infection
– Berberine or tea leaf oil or uvaursi for 3-7 days
With cervical dysplasia
– Echinacea angustifolia – 2 weeks for the night
– Berberine or tea leaf or uvaursi – for 3-7 days
With lung infection
– Bidenspilosa – tincture1/4 teaspoons 3-6x a day
– Mix of Liquorice, elecampane root, yerba santa leaf, lomatium – 1/2 teaspoon 6x daily
– Sidaacuta – tincture 1/2 teaspoon 3-6x daily
– NAC – 4 games a day (sharp!)
– Bidenspilosa – 1/2 teaspoon 6x daily
Hemoplasm with erythrocyte infection
– Sidaacuta – 1/2 teaspoon of tincture 3-6x a day
– Cryptolepsis – 1/2 teaspoon 3-6x daily
– Alchornea – 1/2 teaspoon 3-6x daily
With neuro problems
– Motherwort – tincture 1/2 teaspoon 6x a day
– Greater celandine – tincture 1/4 teaspoon 3x daily
– kudzu root – 1/4 teaspoon 3-4x daily
With neuro problems (damaged nervous system)
– Chinese senega root – 30 drops 3x a day for 30 days
– Lions mane – 3.8 grams per day or 1 teaspoon of tincture 2x a day
With neuro pain
– Greater calendine – tincture 1/4 teaspoon 3x daily
– Kudzu root – 1/2 teaspoon 3-4x daily
– Pasque flower – tincture 10 drops every hour if needed
– Motherwort – tincture 1/2 teaspoon 6x a day
– Coral root – 30 drops 6x a day
With sleeping problems
– Smooth melatonin an hour before bedtime
– Ashwaganda – tincture 1/2 teaspoon one hour before bedtime or 1gram 1 hour before bedtime (extract)
– motherwort – a teaspoon of tincture one hour before bedtime.
To overcome overwork
– Eleutherococcus – tincture 1/4 teaspoon in the morning
– Rhodiola – tincture 1/4 teaspoon in the morning
– Schisandra – tincture 1/4 teaspoon in the morning
– Motherwort – 1/4 teaspoon tincture in the morning
For joint problems
– Greater celandine, olive leaf, berberine, ashwaganda, green tea
– Chondroitin / glucosamine (I personally do not recommend – more placebo for me)
– Milk thistl
For problems with fast weight loss
– Shiitake Mushroom – 6-16grams a day
+ vitamins, amino acids, minerals.e – tincture 1/4 teaspoon 3-6x daily
Byron White protocol (herbal blend)
- oleaeuropaea (leaf) – olive tree leaf
• allium sativum (bulb) – garlic
• actostaphylosuvaursi (leaf) – bearberry leaf
• usneabarbata (lichen) – lichen of usnea
• stillingiasylvatica (root) – stillingiasylvatica root
• uncariatomentosa (bark) – the bark of the fluffy pairs
• uncariarhychophylla (vine with hooks) -Gou Teng / uncariarhychophyll
• bidospilosa (leaf) – leaf of bidenspilosa
• cassia occidentalis (leaf) – cassia occidentalis leaf
Other information on the basis of research what works on mycoplasma:
- Common milkwort (Seneca-snakeroot) – Contains a lot of compounds that act as expectorants, reduce mucus in the respiratory tract. In addition, it has anti-asthmatic, antiseptic, antispasmodic, astringent, soothing and antibacterial properties.
• Common Mullein (Mullein) – has an expectorant effect (removes mucus and congestion), used mostly in the case of problems with the bronchi and lungs such as their inflammation or in asthma, emphysema or allergies. It also has anti-inflammatory effects. It is used for coughing, sore throat, lymphatic blockages, helps to reduce tumors and boils.
• pneumoniae mycoplasma increases interferon gamma levels and lowers the anti-inflammatory cytokine IL-4. Vitamin A lowers overactive gamma interferons and increases IL-4.
• Tea tree leaf oil shows very good performance vs pneumoniae – it is recommended to make mouth and tooth rinses
• Bergamot oil shows a sensational action vs Pneumoniae
• Linalool has very good anti-bacterial properties vs mycoplasma pneumoniae and Mycoplasma fermentans and also works on mycoplasma hominis.
• Mycoplasma stimulates the cytokine IL-18 (it is an inflammatory cytokine from the group of cytokines IL-10), which causes the growth of intra-interferon gamma, NK cells, T-lymphocytes which in the long-term leads to sclerosis, dysplasia, RA or psoriasis as well as cancer or chronic fatigue.
• SPLUNC1 protein is a protein that is reduced by Mycoplasmapneumoniae – its high level contributes to the suppression of this infection. Its high level also reduces the level of eosinophils that cause inflammation. Resveratrol (the highest concentration in Japanese knotweed stimulates SPLUNC1).
• Mycoplasma affects the heart, lungs and CNS (central nervous system) causing chest pain, neuro problems including meningitis, encephalitis or anemia.
• Peppermint oil and eucalyptus oil – they help in the case of inflammation of the respiratory tract and the digestive system as well as in liver diseases. They act on staphylococci MRSA, e.coli, enterococcusa, blue oil rod, candida albicans and reduce inflammation. Patients with Mycoplasma notice reductions in chronic health problems such as muscle, joint, headache, sleep problems, inflammation, fatigue, mental fog and mental disorders.
• Isatidis root (Ban Lan Gen) – eliminates toxins, fever, tonsillitis, upper respiratory tract infections or spots on the skin as well as redness or swelling of the face, encephalitis, hepatitis, smallpox, herpes or shingles. Possible side effects are ailments from the digestive system (allergic reactions may also occur and should be carefully administered to people who take anticoagulants or antiplatelet agents). It has antibacterial properties against mycoplasma hominis, staphylococcus aureus, e.coli, salmonella, influenza virus or leptospira.
• Root from Angelica dahurica (Bai Zhi). Herb used to treat cold symptoms, mucus discharge and pain. Used in nasal congestion, headaches, muscle pain, sinusitis, rhinitis or in the case of white or yellow nasal discharge. reduces inflammation, ulcers, boils, rashes, pruritus, skin ulcers. it is also used in the case of nipple and intestinal abscesses, acute appendicitis or diarrhea. This herb inhibits mycoplasma hominis, e.coli, bacillus dyseneriae, bacillus proteus, salmonella, staphylococcus aureus, mycobacterium tuberculosis, shingelle. In studies, it has anti-inflammatory, analgesic, antipyretic and antispasmodic properties as well as lowers heart rate, increases the depth of breathing and stimulates the nervous system.
• Felodendron (Phelodendron – Phellodendri, Huang Bai) – it is used in the removal of heat (i.e. inflammation) and symptoms of infection, eliminates toxins and thirst, in the treatment of jaundice, diarrhea, feelings of incomplete bowel movement, hemorrhoids, difficulties in passing urine or supports painful and swollen joints. It is also treated with the lower sections of the spine, i.e. the lumbar section and knees or urinary tract infections. It treats fever, tinnitus, dizziness, facial flushes, scant menstruation, uterine bleeding disorders, and lowers blood pressure. It exhibits antibiotic action against Mycoplasma hominis, Staphylococcus aureus, Streptococcus. The leaves of this plant have antiviral activity.