Human granulocyticanaplasmosis (HGA),
is a tick-related disease caused by a bacterial species called Anaplasmaphagocytophilum. HGA is transmitted to humans by tick biting. Is all Anaplasmosis worse from Lyme disease among all coinfections? This is not only the position of ILADS but also the CDC, which stressed that this disease can become infected as a result of a tick bite. A disease that is difficult to diagnose can be quickly annihilated after fast dosing of doxycycline right after biting. Antibodies in this disease usually appear after 7 days, waiting for tests and their results is a heroic fight against time. Anaplasmosis, like Lyme disease, is an intracellular bacterium and its residence time in blood is short.
Anaplasmosis is a co-infection that can lead to permanent disability or death. Unfortunately, there is no characteristic symptom, such as erythema migrans. Doctors in endemic zones generally do not wait for the results of the lab test and introduce antibiotics almost immediately. Sustained, late anaplasmosis (chronic anaplasmosis) always leaves a mark and detriment to health. Sickened patients complain of joint pain, fatigue and drowsiness. This is another proof that doctors even introduce prophylactic treatment at the explicit request of the patient. The more so because it is estimated that 75% of the patients infected Lyme have at least one of the strains of this serious disease.
Clinical symptoms of HGA may range from mild to life threatening depending on the patient’s age and general health. The onset of anaplasmosis usually begins within a week of the tick bite and often includes fever, severe headaches, malaise, muscle aches and chills. Other symptoms may include confusion, haemorrhage and kidney failure. The initial diagnosis is based on the patient’s symptoms and laboratory tests. Routine laboratory results include low white blood cell count, low platelet count and elevated levels of specific liver enzymes. Blood smears can be used to search for the characteristic microcolonies of A. fagocytophilium in infected blood cells. However, the final diagnosis can only be made using PCR (polymerase chain reaction) or immunostaining methods.